Winning Cookie Clicker involves a combination of strategy, upgrades, and efficient resource management. Prioritize purchasing upgrades that enhance your cookie production. Look for upgrades that multiply your cookie output. Invest in buildings that generate cookies automatically. Start with cursors, then move on to grandmas, farms, and so on. Each building has its own strengths. Click on golden cookies whenever they appear. They provide significant boosts or bonuses, like temporary production multipliers or free cookies.